Center for Technology Commercialization

Program: Medical College of Wisconsin UWM Research Foundation

Next-Generation Anxiety Therapeutics

Technology Sectors:

The Opportunity: New Approaches to Treating Anxiety Disorders

Anxiety disorders are common, yet existing treatments, including SSRIs, SNRIs, and benzodiazepines, may provide incomplete relief, act slowly, cause unwanted side effects, or raise concerns about dependence.

The Technology & Current Status

This technology is focused on developing a novel class of therapeutics for anxiety disorders based on a differentiated biological mechanism. The approach targets SCP-2, an endocannabinoid transporter involved in regulating the body’s natural anxiety-response pathways. Drug leads targeting SCP-2 may provide access to a novel therapeutic target while potentially avoiding limitations of existing therapies, including sedation, dependence risk, delayed onset, and neurological side effects. The technology is currently at an early preclinical stage and would benefit from additional translational research, efficacy studies, medicinal chemistry optimization, and commercial development.

Initial Target Applications and Markets

The primary opportunity is developing therapeutics for anxiety disorders, including generalized anxiety disorder, social anxiety disorder, panic disorder, and related conditions. Potential customers and partners include biotechnology companies, CNS-focused pharmaceutical developers, and organizations pursuing novel neuropsychiatric therapies.